Isle of Palms Vacation Rentals with 5+ Bedrooms
When planning a beach getaway for a larger group, East Islands Rentals is here to help. We have a diverse selection of Isle of Palms vacation rentals with 5 bedrooms or more. With homes that accommodate up to 13 guests, there is space and privacy for your group. These larger homes are perfect for those planning a family reunion, a multi-family vacation, a girlfriend’s getaway, or even a corporate retreat.
Each of our vacation rentals feature a well-equipped kitchen, spacious dining areas, large living areas, and fantastic outdoor spaces. Most homes offer expansive decks for dining al fresco or sunbathing.
Browse our selection of Isle of Palms vacation rentals with 5 bedrooms or more, and find one perfect for your South Carolina getaway.
Min Bedrooms : 5
Viewing 21 Results
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FROM $358
- $1169
2201 PALM | THE SURF SHACK | POOL | HOT TUB
Isle of Palms
Beds: 5 | Baths: 5 | Sleeps: 10
FROM $564
- $1640
12 GRAND PAVILION | OCEANVIEW | SUNSHINE BY THE SEA | COMM. POOL
Isle of Palms
Beds: 6 | Baths: 4.5 | Sleeps: 14
FROM $2588
- $3785
610 OCEAN | OCEANFRONT | SEASIDE BEAUTY | POOL
Isle Of Palms
Beds: 11 | Baths: 8 | Sleeps: 28
FROM $1278
- $3554
812 OCEAN | OCEANFRONT | LANDS END | POOL | SPA | ELEVATOR
Isle of Palms
Beds: 6 | Baths: 6.5 | Sleeps: 12
FROM $842
- $2700
2916 PALM | OCEANFRONT | PALM BREEZE | POOL | SPA | ELEVATOR
Isle of Palms
Beds: 6 | Baths: 6.5 | Sleeps: 16
FROM $570
- $2092
902 OCEAN | OCEANFRONT | OCEAN CAMP | POOL | SPA
Isle of Palms
Beds: 6 | Baths: 4 | Sleeps: 14
FROM $640
- $2215
312 OCEAN | OCEANFRONT | OCEAN ESCAPE | POOL | ELEVATOR
Isle of Palms
Beds: 6 | Baths: 4 | Sleeps: 14
FROM $892
- $2785
108 OCEAN | OCEANFRONT | LADY POSEIDON | POOL | SPA | ELEVATOR
Isle of Palms
Beds: 6 | Baths: 5.5 | Sleeps: 18
FROM $607
- $1957
3000 PALM | OCEANFRONT | SAND PIT | SCREEN PORCH | ELEVATOR
Isle of Palms
Beds: 6 | Baths: 6 | Sleeps: 12
FROM $427
- $1542
410 CAROLINA | OCEAN VIEW | CAROLINA DREAM | POOL | ELEVATOR
Isle of Palms
Beds: 5 | Baths: 5 | Sleeps: 13
FROM $820
- $2814
612 OCEAN | OCEANFRONT | BELLA VISTA |POOL | SPA | ELEVATOR
Isle of Palms
Beds: 7 | Baths: 5.5 | Sleeps: 16
FROM $846
- $2057
5 DUNECREST | OCEANFRONT | VIEWS | ELEVATOR
Isle of Palms
Beds: 5 | Baths: 5 | Sleeps: 12
FROM $285
- $1085
9 BEACHWOOD W | OCEAN VIEW | WHISPERING OAKS
Isle of Palms
Beds: 5 | Baths: 3.5 | Sleeps: 12
FROM $500
- $1735
11-55TH AVE | OCEANFRONT | BEACH DAYS | SCREEN PORCH |
Isle of Palms
Beds: 6 | Baths: 5 | Sleeps: 16
FROM $1271
- $4285
110 OCEAN |OCEANFRONT | FIREFLY | POOL | ELEVATOR
Isle of Palms
Beds: 10 | Baths: 11 | Sleeps: 28
FROM $840
- $3378
604 OCEAN | OCEANFRONT | C BREEZE | POOL | ELEVATOR
Isle of Palms
Beds: 8 | Baths: 9 | Sleeps: 19
FROM $395
- $1542
3706 CAMERON | OCEANVIEW | ATTITUDE ADJUSTMENT | POOL | ELEVATOR
Isle of Palms
Beds: 6 | Baths: 4.5 | Sleeps: 12
FROM $564
- $1785
906 OCEAN | OCEANFRONT | PELICAN WATCH | VIEW DECK
Isle of Palms
Beds: 5 | Baths: 3 | Sleeps: 12
FROM $1275
- $3592
816 OCEAN | OCEANFRONT | SAND SERENITY | POOL | SPA | ELEVATOR
Isle of Palms
Beds: 6 | Baths: 7 | Sleeps: 12
FROM $890
- $2764
908 OCEAN | OCEANFRONT | BISHOPS | POOL | ELEVATOR
Isle of Palms
Beds: 7 | Baths: 5.5 | Sleeps: 14
FROM $570
- $1765
216 OCEAN | OCEANFRONT | BEACH HOUSE | SCREEN PORCH | ELEVATOR
Isle of Palms
Beds: 7 | Baths: 5 | Sleeps: 16
Viewing 21 Results